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All Studies   Meta Analysis   Recent: 
Computational Identification of a Putative Allosteric Binding Pocket in TMPRSS2
Sgrignani et al., Frontiers in Molecular Biosciences, doi:10.3389/fmolb.2021.666626
30 Apr 2021    Source   PDF   Share   Tweet
In Silico study of TMPRSS2 inhibition by camostat, nafamostat, and bromhexine, suggesting allosteric binding for bromhexine, compared to camostat and nafamostat which bind to the active site of TMPRSS2 forming covalent adducts.
Sgrignani et al., 4/30/2021, peer-reviewed, 2 authors.
In Silico studies are an important part of preclinical research, however results may be very different in vivo.
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This PaperBromhexineAll
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